The meeting starts on Monday October 16 at 9:00 and closes on Wednesday October 18 at 15:30.
Sessions are listed below.
Each session will include presentations from invited speakers and oral communications selected from submitted abstracts.
9:00 : Welcome coffee
9:45 Session 1 : Keynote lecture
Chair person : Abdou Rachid Thiam & Hubert Schaller (GERLI President)
10:00 Robert V. Farese, Jr. (Keynote speaker, New York, USA): The phase of fat: mechanisms and physiology of lipid storage
11:00 GERLI PhD Award: Romain Magny (Paris, France): Investigating markers of pathophysiological processes of dry eye disease through lipidomic approaches
11:15 GERLI-SFN and SFEL PhD Awards: Jeanne Kergomard (Rennes, France): Enzymatic activity on plant lipids: combination of interfacial measurements at the molecular scale (nm) and kinetic measurements of degradation at the object scale (μm)
11:30 Posters “flash presentations” (chair person: Gerard Lambeau)
12:15 Lunch Buffet and Posters
14:00 Session 2: Lipid trafficking at contact sites
Chair persons : Isabelle Dugail & Abdou Rachid Thiam
14:00 Francesca Giordano (Invited speaker, Gif s/ Yvette, France): Ménage à trois: role of endoplasmic reticulum-mitochondria contact sites in lipid droplet biogenesis
14:30 Claudia Matthaeus (Postdam, Germany): Novel insights in caveolae mediated lipid trafficking
14:45 Heitor Gobbi Sebinelli (Gif-sur-Yvette, France): What roles can the yeast tether Ist2 play at ER-PM contact sites?
15:00 Fabien Alpy (Invited speaker, Strasbourg, France): The MOSPD2 protein connects the Endoplasmic Reticulum to other organelles (endosomes, mitochondria…) … and to Lipid Droplets
15:30 Alicia Damm (Paris, France): “Should I stay or should I go”: protein relocation from ER-to-Lipid Droplets
15:45 Francisco Sarmento Mesquita (Invited speaker, EPFL, Lausanne, Switzerland): Why Lipids and Lipid Modifications are central for the biology of Coronaviruses?
16:15 Coffee break and posters
16:45 Session 3: Lipids in diseases
Chair persons : Gérard Lambeau & Lhousseine Touqui
16:45 Chetan Chitnis (Invited speaker, Paris, France): Targeting a host phospholipase A2 to develop a drug for malaria
17:15 Maria Moriel-Carretero (Montpellier, France): The sterol / PI(4)P exchange at the heart of the increased susceptibility of cancer patients under chemotherapy to fatal SARS-CoV-2 infection
17:30 Lea Loisay (Lausanne, Switzerland): Bone marrow lipids: The Good, the Bad, and the Ugly in Osteoarthritis
17:45 Thierry Durand (Montpellier, France): Oxidized DHA and AdA to Dihomo-Isoprostanes and Neuroprostanes, Biomarkers and Bioactive Oxylipins
18:00 Charlotte Gehin (Lausanne, Switzerland): CERT1 mutations perturb human development by disrupting sphingolipid homeostasis
18:15 Lena Clausmeyer (Osnabrück, Germany): In vitro characterization of the ceramide synthase in S. cerevisiae
18:30 End of day 1, dinner on your own
9:00 Session 4: Cancer and Metabolic diseases
Chair persons : Cécile Gladine & Ez-Zoubir Amri
9:00 James Olzmann (Invited speaker, Berkeley, USA): Mechanisms of lipid quality control and ferroptosis
9:30 Logan Leak (Stanford, USA): Palmitate as a central node in a novel non-apoptotic cancer cell death mechanism
9:45 Perrine Vermonden (Louvain-la-Neuve, Belgium): Phospholipase PLA2G7 is complementary to GPX4 in mitigating punicic acid-induced ferroptosis in prostate cancer cells
10:00 Joel Haas (Invited speaker, Lille, France): Development of Hepatic Inflammation in NAFLD
10:30 Youenn Launay (Rennes, France): Decrypting the mechanisms involved in hepatic steatosis induced by an excess of dietary linoleic acid
10:45 Gwendolyn Barceló-Coblijn (Balearic Islands, Spain): Visceral adipose tissue in the colon cancer microenvironment: a multi-omic approach
11:00 Coffee Break and posters
11:30 Marc Poirot (Invited speaker, Toulouse, France): The biological importance of the C5-C6 double bond of cholesterol
12:00 Jeroen Guns (Diepenbeek, Belgium): Extracellular vesicle-associated cholesterol dictates the regenerative functions of macrophages in the brain
12:15 John Yu (Taoyuan, Taiwan): Dysregulated Fatty Acid Metabolism Drives Cardiomyocyte Remodeling in Arrhythmogenic Cardiomyopathy
12:30 Presentation by sponsor Proteigene/Biocrates: Carlos Malpica & Benoit Sarazin
12:40 Lunch Buffet and Posters
14:00 Session 5: Chemical biology and analysis
Chair persons: Benoit Colsch & Nicolas Vitale
14:00 Maria Fedorova (Invited speaker, Dresden, Germany): Cellular lipidome plasticity in stress responses
14:30 Brian Kleiboeker (St. Louis USA): Shotgun Lipidomic Assignment Tool (SLAT) Processing high resolution mass spectrometric data for rapid identification of lipid structures in mixture by elemental composition database searching
14:45 Jeremy Baskin (Invited speaker, New York, USA): Imaging and Editing the Lipidome
15:15 Alexander Wolf (Strasbourg France): Chemically modified lipids to explore differential roles of various phosphatidic acid species in neurosecretion
15:30 Andrey Klymchenko (Invited speaker, Strasbourg, France): Fluorescent tools to shed light on lipids in plasma membranes and organelles
16:00 Chems Amari (Paris, France): Control of lipid droplet dynamics in cells using engineered compartments
16:15 Bruce Shilito (Invited speaker, Paris, France): Lipidome variations of deep-sea vent shrimps according to acclimation pressure: A homeoviscous response?
16:45 Delphine Vergoz (Rouen, France): Lipidome of Acinetobacter baumannii persister cells
17:00 Coffee & Posters
17:00 GERLI General Assembly
20:00 Gala dinner at “Madame Brasserie”, Eiffel Tower 1st floor
9:00 Session 6: Infection and Immunity
Chair persons : Lhousseine Touqui & Jérôme Nigou
9:00 Nina Van Sorge (Invited speaker, Amsterdam, The Netherlands): Empowering human secreted phospholipase in anti-bacterial defense
9:30 Jeroen F.J. Bogie (Diepenbeek, Belgium): Stearoyl-CoA desaturase-1 impairs the regenerative and anti-inflammatory properties of microglia and T cells in the brain
9:45 Khaled Tighanimine (Paris, France): Glycerol-3-phosphate and Phosphoethanolamine homeostatic switch triggers senescence by rewiring lipid metabolism
10:00 Ivo Gomperts Boneca (Invited speaker, Paris, France): When fat makes you happy
10:30 Sharon Wein (Montpellier, France): The two first steps of the Kennedy phosphatidylcholine pathway are essential for the survival of the malaria parasite
10:45 Inês Guerra (Aveiro, Portugal): Assessing Lipid Modulation in Medium-Chain Acyl-CoA Dehydrogenase Deficiency through Plasma Lipidomics Analysis
11:00 Coffee Break
11:30 Session 7: GERLI/SFN: Lipids and nutrition
Chair persons : Sylvie Demignot & Olivier Laprevote
11:30 Marie Caroline Michalski (Invited speaker, Lyon, France): Metabolic impacts of dietary polar lipids according to their specific residues in the gut
12:00 Olivier Briand (Lille, France): Enterocyte lipid absorption is controlled by nuclear receptor NR1D1 regulation of IQGAP2-mediated cytosolic lipid droplet mobilization
12:15 Raquel B. Gómez-Coca (Seville, Spain): Mineral oil hydrocarbons in olive oils: analysis and health
12:30 Christophe Magnan (Invited speaker, Paris, France): Brain lipid sensing and control of energy balance
13:00 Vincent Ciesielski (Rennes, France): May dietary pentadecanoic acid (C15:0) prevent physiological symptoms induced by a linoleic acid (C18:2 n-6) deficient diet in the rat?
13:15 Julia Kuligowski (Valencia, Spain): Identification of oxylipins in human milk-derived extracellular vesicles with pro-resolutive potential in gastrointestinal inflammation
13:30 Poster and Short talk prize, Closure, and Departure & Catering (distribution of lunch boxes)
