*please note that session order has been changed to fit with speakers’availability


Sunday, september 30th, 2018 – Opening session

14:00-18:00      Registration of participants

18:00-18:15      Opening by local organizers and welcome talks

18:15-19:15      Opening lecture: Christoph Benning (Michigan State University, USA
                          A role for lipid droplets in membrane lipid remodelling

19:15-               Welcome reception – Drinks, Buffet

Monday, October 1st, 2018 – Morning session

  1. The lipid droplet: from biophysics to metabolism

Chairs: Véronique Vié (Rennes University, France) and Tim Wooster (Nestlé RC, Switzerland)

09:00-09:30      Keynote: Abdou Rachid Thiam, (CNRS and ENS Paris, France)
                        Membrane ingredients for making cytosolic lipid droplets

09:30-09:45      Alain Geloen (CarMeN Laboratory, Lyon, France)
                        Label free quantification of lipid droplets in live cells

09:45-10:00      Franziska K. Kretzschmar (Georg-August-University Göttingen, Germany)
                        A lipid droplet-associated scaffold protein important for protein degradation in seedlings
                        of Arabidopsis thaliana

10:00-10:15      Sabine D’Andrea (INRA, AgroParisTech, France)
                        PUX10 associates with CDC48A and regulates the extraction of ubiquitinated oleosins
                        from seed lipid droplets

10:15-10:45      Coffee break – Posters

10:45-11:15      Keynote: Nurit Argov-Argaman (The Hebrew University of Jerusalem, Israel),
                         Metabolic regulation of milk fat globule size; Novel targets for improving milk quality

11:15-11:30      Claire Bourlieu (INRA, UMR IATE Montpellier, France)
                        Imaging lipase activity on milk fat globules using tryptophane autofluorescence
                        and UV microscope at DISCO beamline

11:30-11:45      Josselin Lupette (CEA Grenoble, France)
                        Development, Architecture, and Dynamics of lipid droplets in the pennate                        
                        diatom Phaeodactylum tricornutum

11:45-12:00      Valentina Guerrini (Rutgers, The State University of New Jersey, USA)
                        Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific

12:00-14:00      Lunch – Posters

Monday, October 1st, 2018 – Afternoon session

  1. Lipid biosynthesis in plants and microorganisms for bioenergy, green chemistry and nutrition

Chairs: Brigitte Gontero (CNRS, Marseille, France) and Hubert Schaller (CNRS, Strasbourg, France)

14:00-14:30      Keynote: Eric Maréchal (CNRS and CEA, Grenoble, France)
                        Role of nitric oxide in nitrogen and lipid homeostasis in the diatom Phaeodactylum

14:30-14:45      Laura Prioretti (Aix Marseille University, CNRS, France)
                        The inhibition of the target of rapamycin in Phaeodactylum tricornutum:
                        a new route toward the sustainable generation of biofuel from microalgae

14:45-15:00      Adrien Burlacot (CEA Cadarache, CNRS, Aix-Marseille University, France)
                        Increasing lipid droplet formation and carbon fixation in microalgae through modulating
                        redox communication between peroxisome and chloroplast

15:00-15:15      Uri Pick (The Weizmann Institute of Science, Rehovot, Israel)
                        The origin of carotenoid lipid globules in green algae

15:15-15:45      Coffee break – Posters

15:45-16:15      Keynote: Inna Khozin-Goldberg (Ben-Gurion University of the Negev, Israel),
                         Microalgal lipid droplets as reservoir for high value molecules

16:15-16:30      Claire Vigor (CNRS, Montpellier University, France)
                        Quantification and characterization of isoprostanoids from three microalgae species
                        produced at 5 000 L scale

16:30-16:45      Gustav Waschatko (Cargill R&D Centre Europe, Belgium)
                        Blending Oleosomes – Playing with natural plant Emulsions to influence Texture

16:45-17:00      Damien Sorigué (CEA Cadarache, CNRS, Aix-Marseille University,France)
                        Structure-function studies of a fatty acid photodecarboxylase

17:00-17:30      Short talks for poster presentations

17:30-19:00      GERLI General Assembly

17:30-19:00      Guided tour of St Maximin’s Basilica and Royal Convent: Isabelle Arlery
                        (in English)

19:00-              Free evening

Tuesday, October 2nd, 2018 – Morning session

  1. Enzymes in lipid modification

Chairs: Pierre Villeneuve (CIRAD Montpellier, France) and Gérard Lambeau (IPMC, CNRS, Valbonne Sophia Antipolis, France)

09:00-09:30      Keynote: Monika Oberer (University of Graz, Austria)
                        Protein-protein interactions regulate the activity of Adipose Triglyeride Lipase
                        in intracellular lipolysis

09:30-09:45      Isabelle Dugail (INSERM, Sorbonne University, Paris, France)
                        Lysosomal acid lipase knockdown affects adipocyte storage through                               
                        cholesterol-dependent ER/lipid droplet dynamics, independent of lipophagy

09:45-10:00      Ismael Torres-Romero (CEA Cadarache, CNRS, Aix-Marseille University, France)
                        Unveiling the function of a lipid droplet-associated α/β-hydrolase in Chlamydomonas

10:00-10:15      Till Ischebeck (Georg-August-University Göttingen, Germany)
                        Investigation of a family of LD-associated Lipases from Arabidopsis thaliana

10:15-10:45      Coffee break – Posters

10:45-11:15      Keynote: Toni Petan (Jožef Stefan Institute, Ljubljana, Slovenia)
                        Lipid droplets balance fatty acid trafficking with cell survival mechanisms                        
                        and protect cancer cells from nutrient and lipotoxic stress 

11:15-11:30      Rolf K. Berge (University of Bergen, Norway)
                        Increased hepatic mitochondrial fatty acid oxidation and decreased gene expression
                        of Dgat2 lead to reduced liver steatosis in rat

11:30-11:45      Solène Moulin (CEA Cadarache, CNRS, Aix-Marseille University, France)
                        Study of the biodiversity and physiological role of a hydrocarbon-forming enzyme
                        in microalgae

11:45-12:00      Imogen Foubert (KU Leuven, Belgium)
                        Lipolytic stability during wet storage of autotrophic microalgae

12:00-14:00      Lunch – Posters

Tuesday, October 2nd, 2018 – Afternoon session

  1. Lipidomics, lipid imaging and trafficking in membranes and lipid droplets

Chairs:  Frédéric Domergue (CNRS, Villenave d’Ornon, France) and Michel Record (INSERM, Toulouse, France)

14:00-14:30      Keynote: Kent Chapman (University of North Texas, USA)
                        New players in plant lipid droplet biology

14:30-14:45      Claire Bréhélin (LMB, CNRS, Villenave d’Ornon, France)
                        Proteomics of leaf lipid droplets reveal new proteins involved in LD biogenesis

14:45-15:00      Denis Coulon (LMB, CNRS, Villenave d’Ornon, France)
                        C16:3 and C18:3 coming from MGDG degradation segregate respectively                        
                        in plastidial and cytosolic lipid droplets in response to Nitrogen starvation

15:00-15:15      Natasa Petrovic (Wenner-Gren Institute, Stockholm University, Sweden)
                        A lipid droplet protein Cidea inhibits UCP1 activity by an indirect mechanism

15:15-15:45      Coffee break – Posters

15:45-16:15      Keynote: Alenka Čopič (CNRS, Institut Jacques Monod, Paris, France)
                        A giant amphipathic helix that coats lipid droplets

16:15-16:30      Bertrand Mollereau (Lyon University, ENS Lyon, France)
                        Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila
                        and mice retina

16:30-16:45      Nicolas Vitale (CNRS, Strasbourg University, France)
                        Lipidomic and functional analysis reveal distinct roles for mono and poly-unsaturated
                        lipids in regulated exocytosis

16:45-17:00      GERLI PhD award: Léa Wilhelm (IGBMC, Illkirch, France)
                        STARD3, a new actor in cellular cholesterol trafficking

17:00-17:15      GERLI PhD award: Matthieu Platre (Lyon University, ENS Lyon, France)
                        Localization and function of anionic lipids in cell organization and plant development

17:30-19:00      Guided visit of St Maximin’s Basilica and Royal Convent: Isabelle Arlery
                        (in French)

19:30-22:00      Gala Dinner

Wednesday, October 3rd, 2018 – Morning session

  1. Lipid droplets in the gut: from digestion of dietary lipids to oral lipid-based drug delivery systems

Chairs: Vincent Rioux (Agrocampus, Rennes, France) and Xavier Collet (INSERM, Toulouse, France)

08:30-09:00      Keynote: Tim Wooster (Nestlé RC, Switzerland)
                        Gastric structured emulsions: A simple way to alter lipid absorption kinetics

09:00-09:15      Isabel Medina (Instituto de Investigaciones Marinas, CSIC, Vigo, Spain)
                        Amounts of DHA in marine oils affect digestion and intestinal absorption of lipids

09:15-09:30      Christime Coméra (INRA,Toulouse, France)
                        Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets                     
                        near the brush border membrane

09:30-09:45      Marielle Margier (Aix Marseille University, INSERM, INRA, C2VN, Marseille, France)
                        Phytates, saponins, tannins and fibers from legumes alter fat-soluble vitamin

09:45-10:00      Emmanuelle Reboul (Aix Marseille University, INSERM, INRA, C2VN, Marseille, France)
                        ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to                        
                        its transintestinal efflux

10:00-10:30      Coffee break – Posters

10:30-11:00      Keynote: Vincent Jannin (Gattefossé, France),
                        SEDDS – Self-emulsifying lipid droplets to enhance the solubility, stability,                        
                        and absorption of poorly orally-bioavailable drugs

11:00-11:15      Marie-Caroline Michalski (INRA, INSERM, Lyon University, France)
                        Polar Lipids of the Milk Fat Globule Membrane Reduce Cardiometabolic                          
                        Risk Factors in Postmenopausal Wome

11:15-11:30      Etienne Guillocheau (Laboratory of Biochemistry and Human nutrition, Agrocampus-
                        Ouest, Rennes, France)
                        Trans-palmitoleic acid, a ruminant dairy fat biomarker, and metabolic                              
                        syndrome components: a nutritional study on mice

11:30-11:45      Mélanie Le Barz (Laval University, Québec, Canada)
                        Transgenic production of endogenous n-3 PUFA levels compared to fish oil intake       
                        differentially improve obesity-related metabolic disorders: role of the gut microbiota

11:45-14:00      Lunch and Departure


Posters will be exposed during the whole duration of the meeting, at the same place as coffee breaks and lunches (12:00-14:00 on Monday and Tuesday), so that they can be seen during these breaks. We ask the presenting authors to remain close to their poster during these periods, at least from 13:00 to 14:00 on Monday and Tuesday, so that they can present their work to the committee in charge of the best poster award.

In addition, poster presenting authors are requested to attend the “Poster flash presentations” session on Monday October 1st, at 17:00 to present their poster orally. Their flash talk is limited to 1 min, with a maximum of 2 slides.

POSTER 1: Using the Tracker™ drop tensiometer for measuring transfer of tensioactive molecules between two drops
Anaïs Bénarouche1, Jean-Luc Bridot1, Frédéric Carrière2 and Alain Cagna1 (Sponsor – TECLIS)

POSTER 2: The role of LDIP in regulating lipid droplet size and neutral lipid homeostasis in plant cells
Michal Pyc1, Satinder K. Gidda1, Yingqi Cai2, Michael S. Greer2, Franziska K. Kretzschmar3, Damien Seay4, Joe Hull4, Till Ischebeck3, Kent D. Chapman2,
John M. Dyer4, and Robert T. Mullen1

POSTER 3: Two newly identified lipid droplet proteins affect lipid droplet arrangement in germinating Arabidopsis thaliana seeds
H. Elisa Krawczyk1, Franziska K. Kretzschmar1, and Till Ischebeck

POSTER 4: Arabidopsis AT3G11620 is an evolutionarily conserved protein important for the proper distribution and abundance of lipid droplets
Satinder K. Gidda1, Samantha C. Watt1, Marina Mehling2, Vinay Pattalachinti2, Joe Hull2, Kent D. Chapman3, John M. Dyer2 and Robert T. Mullen1

POSTER 5: Modeling of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) with iPSC-derived Cardiomyocytes Containing Lipid Droplets
John Yu

POSTER 6: Understanding of temperature-induced lipid turnover between membrane and neutral lipids in oleaginous microalgae
Hyung-Gwan, L1, Jun-Woo, L1, 2, Hee-Mock, O1*

POSTER 7: Interplay between catabolism of branched-chain amino acids and triacylglycerol homeostasis in Chlamydomonas reinhardtii
Yuanxue, Lianga, Fantao Konga, Ismael Torres-Romeroa, Adrien Burlacota, Stéphan Cuinea, Bertrand Légereta, Saleh Alseekhb, Alisdair R Fernieb, Fred Beissona, Gilles Peltiera, Yonghua Li-Beissona,*

POSTER 8: Seipin overexpression leads to accelerated accumulation of lipid droplets in Phaeodactylum tricornutum
Lebon A., Lupette J., Jouhet J., Maréchal E. and Salvaing J.

POSTER 9: Hypersterolemic lipid bodies of plants
1,4Berna A, 1Mercier P, 3Schaeffer C, 3Strub JM, 1Heintz D, 1Bach TJ, 1,4Hemmerlin A, 3,4Darnet S, 1,4Schaller H.

POSTER 10: Towards understanding the lipid metabolism and fatty acid regulation in Linseed: Metabolomic and Fluxomic approaches
 1Anthony DEGOURNAY, 1Sébastien ACKET, 1Franck MERLIER, 1Manuel Adrian Troncoso-Ponce, 1*Brigitte THOMASSET

POSTER 11: Isoprostanoids quantitative profiling of macroalgae submitted to copper stress
Vigor C.1*, Reversat G.1, Rocher A.1, Oger C.1, Galano J-M.1, Vercauteren J.1, Durand T.1, Tonon T. 2, Leblanc C.3 and Potin P.3

POSTER 12: Behaviour of the Fatty Acid Photodecarboxylase towards lipid/water interfaces
Aselmeyer C.1 ,2, Blangy S.2, Sorigué D.2, Légeret B.2, Cuiné S.2, Beisson F.2,   Carrière F.1

POSTER 13: Deciphering lysosomal enzymatic activities involved in the processing of mycobacterial antigenic glycolipids
Carrat C.1, Dessaux C.1, Carrière F.2, Vergne I.1, Gilleron M.1

POSTER 14: IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids
Moulay Sahaka1, Eduardo Mateos-Diaz1, Priscila Sutto-Ortiz1,2 and Frédéric Carriere1

POSTER 15: The C-terminal end of Yarrowia lipolytica LIP14 lipase is involved in a new mechanism of lipase activation
Amal Salhi1,2, Frédéric Carrière1 and Ahmed Aloulou2

POSTER 16: Identification and quantification of phytoprostanes, phytofurans in coffee and cocoa by- and co-products
Mariana Ruesgas-Ramón1, Claire Vigor3, Amandine Rocher3, Guillaume Reversat3, Joseph Vercauteren3, Camille Oger3, Jean-Marie Galano3, Thierry Durand3, Erwann Durand 2, Maria Cruz Figueroa-Espinoza1.

POSTER 17: Development of an Amide Column-Based LC-MS/MS Method for High-Throughput Targeted Lipidomics
Claire Levasseur (Sponsor – SCIEX),1 Junhua Wang2, Lijuan Fu2, Santosh Kapil Kumar Gorti3, Mackenzie J Pearson2, Sean Wu2, Lei Xiong2 and Paul RS Baker2

POSTER 18: Coupling MALDI mass spectrometry imaging and transcriptomics to study the molecular mechanisms involved in the embedding of lysophosphatidylcholine in starch granules of maize endosperm
Marion, D., Gayral, M., Fanuel, M., Dalgalarrondo, M., Elmorjani, K., Rogniaux, H., Bakan, B.

POSTER 19: HPTLC/MS : a powerful tool for qualitative and quantitative analysis of eicosanoids, generated in lipid droplets
Jérémy Mercier1, Mohamad Alaeddine2, Agnès Coste2, Marie Salon2 (Sponsor – CHROMACIM)

POSTER 20: HPTLC and current application in the lipids study. An overview of a useful analytical tool
Jeremy Mercier1, Pierre Bernard-Savary¹ (Sponsor – CHROMACIM)

POSTER 21: Protecting polyunsaturated fatty acids against in vitro biohydrogena­tion by use of polyphenol-oxidase-mediated cross-linking of emul­sions
N. De Neve,1* B. Vlaeminck,1 F. Gadeyne,1 P. Van der Meeren2 and V. Fievez1

POSTER 22: Impact of the addition of lecithins in oil on the expression of genes involved in intestinal lipid absorption: a preliminary study
Robert C,1,2 Buisson C,1 Meugnier E,1 Loizon E,1 Couëdelo L,2 Laugerette F,1 Vaysse C,2 Michalski MC1 *

POSTER 23: Bioaccessibility of lipophilic nutrients in a chloroplast-rich fraction (CRF) recovered from post-harvest, pea vine field residue (haulm)
Wattanakul Jutarat, Mansor Syamila, Gray David

POSTER 24: Control of adipogenesis and britening by fatty acid metabolites
Colson C.1 and Amri EZ.1

POSTER 25: Omega-3 PUFAs and isoprostanoids regulate inflammation in microglial cells
Roy J.1, Vigor C.2, Rodaros D.1, Rocher A.2, Reversat G.2, Oger C.2, Galano J-M.2, Vercauteren, J.2; Durand T.2, Fulton S.1 and Alquier T.1

POSTER 26: Osteoporosis is associated to high levels of palmitoleate in rat femurs: a preliminary study
During A., Coutel X., Penel G., Olejnik C.

POSTER 27: Dairy products as main dietary sources of trans-palmitoleic and trans-vaccenic acid in France
Guillocheau E1,2*, Penhoat C1, Godet A1, Catheline D1, Legrand P1, Rioux V1

POSTER 28: Improved taste of tomato fruit by lipid landscape manipulation
Anastasiya Kuhalskaya1, Saleh Alseekh2, and Yariv Brotman1

POSTER 29: transAnethole loaded cyclodextrin inclusion complex and conventional liposomes: physicochemical characteristics and antibacterial activity
NAJJAR Amal1, Kfoury Miriana1,2, Fourmentin Sophie2, Greige-Gerges Hélène1, Auezova Lizette1

POSTER 30: Elucidating the role of 3-OH fatty acids in the pathogenicity of Pseudomonas aeruginosa
Evodia Y. Kgotle, Carolina H. Pohl, Jacobus Albertyn and Olihile M. Sebola


Our sponsors